Advanced Longevity Panel

Deep Genetic Insights for Cellular Longevity Optimization
  • Supports Longevity
  • 57 SNPs over 50 genes and 10 traits assessed for comprehensive genetic health insights.

  • Testing on gene variants that impact epigenetic aging, nutrient sensing, and cellular detox pathways in the body 

  • Supports high-level clinical personalization for cognition, metabolism, and metabolic resilience 

  • Empowers practitioners and clients to understand their bodys ability for autophagy, senescence cell clearance, and protein homeostasis. 

  • Ideal for advanced aging, biohacking, and high-performance assessments  

Item:
XTME9131

Technical Bulletin - Practitioner

Technical Bulletin - Client

 

The Premier Advanced Longevity Panel offers a highly detailed look at the cellular mechanics of aging, providing advanced genomic insights across five major domains that extend far beyond traditional aging markers. Designed for high-level bioindividualization, this test supports optimized interventions across detoxification, cognitve, metabolic , and structural resilience 

The Five Major Domains this test assess includes: 

1. Epigenetic Clocks & Age Acceleration 
Evaluates gene variants that explore the genetic blueprint behind the rate of biological aging, focusing on Cellular Senescence, Altered Cell Communication, and Epigenetic Alterations. These pathways are key regulators of DNA expression, mitochondrial health, and systemic inflammation. Insights may lead to use of methylation, antioxidant, and time-restricted eating opportunities to support healthy expression of longevity genes (e.g., TERT, MIR29B2CHG) and autophagy pathways 

2. Nutrient Sensing Dysregulation 
Aging affects how the body detects and uses nutrients. The genes assessed includes key variants that are directly tied to insulin regulation, cardiovascular signaling, calcium metabolism, and the maintence of mitochondrial cofactors like CoQ10 in the body. Markers such as IGF1, GCKR, and CYP24A1, may inform the use of formulas that support Bone Health and metabolic responsiveness in the body. 

3. Proteostasis Imbalance & Cellular Stress 
Proteostasis is the body’s ability to maintain healthy protein structure and clearance. The ability declines with age, which can contribute to neurodegeneration and mitochondrial burden. This section assess genes such as CAST, CPA6, and DDIT4L-AS1 which can guide support strategies including HIIT, sauna, and targeted use of nutrition to support the body’s ability to manage stress and effectively repair proteins. 

4. Autophagy Activation Potential 
This section of the panel evaluates genetic predispositions affecting the body’s innate detoxification and recycling systems, particularly as it pertains to mitophagy and macroautophagy. Genes like ATG16L1, ATG4B, and INPP5D are assessed to predict autophagic capacity, which based on the results may suggest clinical protocols including intermittent fasting, polyphenol intake, and overall antioxidant intake.  

Our advanced panel is ideal for clients seeking precision longevity strategies or experiencing metabolic stagnation, cognitive fatigue, or the decline of physical performance.  

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. 

FAQs
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